Senior Research Fellow (Senior Chemist: siRNA scaffold design and Analytics Development)
Job post no longer accepts applications
The School of Chemistry, Chemical Engineering and Biotechnology (CCEB) invites applications for the position of Senior Research Fellow (Senior Chemist: siRNA scaffold design and Analytics Development).
The main job scope of the Senior Chemist is 1. siRNA scaffolds design, 2. Preclinical evaluation with respect to their effects on activity, stability, specificity and biosafety and 3. their analytic method development. The Senior Chemist will support operations related to oligonucleotide synthesis, ensuring efficient and accurate production of high-quality oligonucleotides and their chemically modified entities. This role involves working with a team of scientists, developing new and optimizing synthesis protocols in oligo modifications and conjugation, managing resources effectively, and fostering a culture of continuous improvement and innovation in oligonucleotide synthesis processes. This role aligns with the University's key research pillar of Future Health.
Key Responsibilities:
Job Requirements:
We regret that only shortlisted candidates will be notified.
Hiring Institution: NTU
The main job scope of the Senior Chemist is 1. siRNA scaffolds design, 2. Preclinical evaluation with respect to their effects on activity, stability, specificity and biosafety and 3. their analytic method development. The Senior Chemist will support operations related to oligonucleotide synthesis, ensuring efficient and accurate production of high-quality oligonucleotides and their chemically modified entities. This role involves working with a team of scientists, developing new and optimizing synthesis protocols in oligo modifications and conjugation, managing resources effectively, and fostering a culture of continuous improvement and innovation in oligonucleotide synthesis processes. This role aligns with the University's key research pillar of Future Health.
Key Responsibilities:
- siRNA scaffolds design and chemical modifications (ie. phosphonate, ribose and base)
- Preclinical evaluation with respect to their effects on activity, stability, specificity and biosafety (eg. siRNA extraction and knockdown studies, quantification of Ago2-loaded siRNA, Ago2 half-life determination, etc)
- Analytic method workflow establishment of analytic method workflow.
Job Requirements:
- PhD in chemistry and relevant fields
- Demonstrated track record in siRNA scaffold design, chemical modification, preclinical evaluation and siRNA analytics process development esp in HPLC and LCMS
We regret that only shortlisted candidates will be notified.
Hiring Institution: NTU
JOB SUMMARY
Senior Research Fellow (Senior Chemist: siRNA scaffold design and Analytics Development)
Singapore
2 months ago
N/A
Full-time