Research Fellow in the Lab of A/Prof Juan Pablo Bifani

NATIONAL UNIVERSITY OF SINGAPORE| Date Posted: 21-Aug-2019
Job Nature:
Contract
Position Level:
Experienced, Manager

Job Description

Roles & Responsibilities

The National University of Singapore invites applications for Research Fellow in the Department of Microbiology and Immunology, Yong Loo Lin School of Medicine. The research on antimicrobial resistance aims to identify the impact of drug resistance on bacterial fitness and host immune response.

Purpose of the post

We seek an enthusiastic and self-motivated research fellow (Post-doctoral position) to join our team. The candidate will join an experienced team working on a project aimed at understanding the impact of drug resistance on bacterial fitness and host immune response in Mycobacterium tuberculosis infections. The candidate should hold a PhD with academic background in Life Sciences and relevant experience in molecular biology, immunology and cell biology. Previous experience working with mice would be highly advantageous. The candidate should be able to work independently, with the ability to work in a dynamic team of the laboratory.

Main duties and responsibilities

The candidate will be expected to lead the design and implementation of a project consisting in engineering recombinant Mycobacterium tuberculosis resistant to selected anti-tuberculars in a Biosafety 3 environment (BSL3). These recombinants are to be evaluated for bacterial fitness in vitro and in vivo using mouse models. The impact on host immune responses will also be determined

Requirements

Qualifications  

The applicant should have a PhD in Life Sciences or related disciplines with a background in molecular biology and infectious diseases and expertise on Mycobacterium tuberculosis.

• Expertise in working with mice is highly desirable

• Experience in working with cell culture and immunology background

• Competency in molecular biology, including genetic recombineering, RT and qPCR, ELISA, Flow cytometry and microscopic techniques

• Excellent writing and presentation skills

• Ability to work independently and on team projects

• Ability to manage/supervise projects

 

Formal application: Please submit your application, indicating current/expected salary, supported by a detailed CV (including personal particulars, academic and employment history, complete list of publications/oral presentations and full contacts of 3 referees.

We regret that only shortlisted candidates will be notified